Search on:
6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE
Descriptors Found:
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DeCS
Descriptor
English
:
Phosphofructokinase-1, Muscle Type
Descriptor
Spanish
:
Fosfofructoquinasa-1 Tipo Muscular
Descriptor
Portuguese
:
Fosfofrutoquinase-1 Muscular
Synonyms
English
:
6-Phosphofructokinase, Muscle Type
Tree Number:
D08.811.913.696.620.225.850.500.500
Definition
English
:
An allosteric enzyme that regulates
glycolysis
by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In
humans
,
PHOSPHOFRUCTOKINASE-1
in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause
GLYCOGEN STORAGE DISEASE TYPE VII
, also known as Tarui's
disease.
Entry Combination - descr/qualif
English
:
Phosphofructokinase-1, Muscle Type
/
deficiency
use
Glycogen Storage Disease Type VII
History Note
English
:
2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
36114
Unique Identifier:
D025203
Occurrence in VHL
:
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